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A liver biopsy is a procedure in which a small piece of liver is removed from the liver to investigate the cause of liver disease. It can be taken subcutaneously, laparoscopically, and intravenously. When is a liver biopsy performed? If liver disease is not diagnosed by other blood tests and imaging methods, a liver biopsy is required. A liver biopsy can be diagnosed with some liver diseases include: hepatitis B hepatitis C conical, autoimmune hepatitis, hemochromatosis, Wilson's disease after liver transplant rejection, Alpha-1 anti-thyroxine deficiency storage disease, how to prepare for a liver biopsy? Before surgery, drugs and sedatives that destroy blood clotting should be stopped. (Aspirin, Coumarin) PTZ and INR, bleeding time, clotting time should be checked before surgery. Patients with liver disease often tend to form blood clots.
To facilitate the operation, mild tranquilizers can be used on the patient prior to the operation. Oral medications or foods should be discontinued for 8 hours before calming the patient. For this reason, patients are prohibited from driving after the operation. How is a liver biopsy performed? A percutaneous liver biopsy can be done using ultrasound or tomography to determine the position. In addition, a needle biopsy forceps biopsy can be performed in the highest mature area by tapping the finger. During the biopsy, the patient lies on his back and stands under his right hand. A biopsy is performed from the lower edge of the rib closest to the defined point. Before the biopsy, numb this area of the ribs, and then make a small incision (skin capsule). During the biopsy, the patient exhales for some time. Therefore, the process is not affected by the Up-Down movement of the liver during respiration.
Venous liver biopsy
This method is used for patients with blood clotting problems or excessive abdominal acid. The neck vein area of the neck is numb, and after a small incision, a sheath (special plastic sheath) is inserted into the vein. Special needle biopsy forceps can be passed through the sheath. The sheath, which passes through the heart, reaches the hepatic vein (hepatic vein), from which it reaches the liver tissue and a biopsy is performed. Follow the patient for four to six hours to check for bleeding.
Laparoscopic liver biopsy
If a biopsy is required from more than one area, you can choose this method. A laparoscopic liver biopsy can be performed if any pathology is found in the liver when laparoscopic surgery is performed for other reasons. In laparoscopic surgery, a small catheter is used to inject air into the abdomen to expand the abdomen. Intra-abdominal surgery and liver biopsy can be performed without large incisions with the help of small cameras and small tools. How is a liver biopsy evaluated? A liver biopsy was examined by the pathology department. Materials covered with special dyes and examined with thin sections are examined by a pathologist. Clinicians should alert pathologists at suspicious spots so that different special dyes can be used. For example, Prussia's blue sky is used for hemochromatosis, the rhodamine dye is used for Wilson's disease, and the rust enzyme dye Alpha 1 is used for antithrosine deficiency.
A liver biopsy is examined by the pathology department. Materials that are painted with special dyes and examined with thin sections are examined by pathology specialist ece. The clinician should warn the pathologist at the points he suspects, accordingly it can be applied in different special dyes. For example, Prussian blue semavisi for hemochromatosis, rhodamine dye for Wilson's disease, rust-diastase dyes for alpha 1 anti-trypsin deficiency are required.